Additional advice
Additional advice
Supply considerations for Gina Local Oestrogen Therapy
Gina is for the treatment of vaginal atrophy due to oestrogen deficiency in postmenopausal women, aged 50 years and above, who have not had a period for at least 1 year – you can use the Gina checklist to assess suitability including contraindications. Refer customers with the following symptoms to their GP for investigation:
Vaginal symptoms
Undiagnosed bleeding
Smelly, or unusual vaginal discharge
Severe vaginal itching (for example, that interferes with sleep)
-
Any changes to the look or feel of the vulva, such as:
Sore red patches
Thickening, a lump or scarring
Itchy, white, smooth/crinkled
Patches of skin easily damaged
A rash.
Other symptoms
Pelvic pain or pain on urination
Lower abdominal pain, bloating or swelling.
Dosage instructions
Initial dose: One vaginal tablet daily for two weeks
Maintenance dose: One vaginal tablet twice a week
If treatment stops, oestrogen will gradually decline and symptoms may return.
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2.Simon J et al. Obstet Gynecol 2008; 112: 1053-60
3.Panay N et al. Menopause International 2012; 18:15-19
4.Nappi RE et al. Maturitas 2016;91:81-90.
5.Kingsberg SA et al. Menopause 2019;26:124-131.
6.Nappi RE et al. Climacteric 2018;21(4):397-403.
7.Palacios S et al. Climacteric 2018;21(3):286-291
8.Office for National Statistics. Available from: https://www.ons.gov.uk/peoplepopulationandcommunity/populationandmigration/populationestimates/datasets/populationestimatesforukenglandandwalesscotlandandnorthernireland.[Accessed Nov 2024].
9.Novo Nordisk. Pharmacy Guide for the Supply of Gina. 2024. Available at: http://www.medicines.org.uk/emc/rmm/2509/Document
10.Hosseinzadeh et.al. J Res Med Sci. 2015 Dec;20(12):1160
11.SmPC. Gina 10 micrograms vaginal tablets. 2024. Available at: http://www.medicines.org.uk/emc/product/13930/smpc/print
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UK24GIN00119 January 2025